| Issue |
Vis Cancer Med
Volume 4, 2023
|
|
|---|---|---|
| Article Number | 7 | |
| Number of page(s) | 7 | |
| DOI | https://doi.org/10.1051/vcm/2023003 | |
| Published online | 04 July 2023 | |
Clinical Case Study
The first reported case of a patient with small cell lung cancer treated with fan beam computed tomography-guided online adaptive radiotherapy
1
Department of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China
2
Shenzhen United Imaging Research Institute of Innovative Medical Equipment, Shenzhen 518048, China
3
Shanghai United Imaging Healthcare Co., Ltd, Shanghai 201807, China
4
United Imaging Research Institute of Intelligent Imaging, Beijing 100094, China
* Corresponding author: chenming@sysucc.org.cn
Received:
24
February
2023
Accepted:
7
June
2023
Adaptive radiotherapy (ART) allows control of dosimetric impact of patient anatomical and functional variations over the treatment course, to minimize normal tissue exposure and maximize dose delivery to tumor. We present the first reported case of fan beam computed tomography (FBCT)-guided online ART for the treatment of small cell lung cancer (SCLC). A 62-year-old woman was diagnosed with histologically proven limited-stage SCLC. During definitive radiochemotherapy (50 Gy in daily fractions of 2.5 Gy), the tumor shrinkage resulted in an unexpected dose escalation to organs at risk (OAR). To correct the dose change, she received an online ART treatment session in our center with four-dimensional FBCT before the 12th fraction was delivered. The application of online ART, including imaging, recontouring and replanning, was feasible as the total treatment time was <25 min. Further research is warranted to verify the benefit of online ART in individualized treatment.
Key words: Online adaptive radiotherapy / Small cell lung cancer / Fan beam computed tomography / Organs at risk
© The Authors, published by EDP Sciences, 2023
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