Open Access
Table 1
Clinical trials on miRNA-based cancer treatment.
| Strategies | miRNA | Drug | Cancer type | Phase | ClinicalTrials.gov ID |
|---|---|---|---|---|---|
| Targeting oncomiR | miR-155 | Cobomarsen | Cutaneous T-cell lymphoma | Phase 2 | NCT03837457 |
| Cutaneous T-cell lymphoma/Mycosis fungoides | Phase 2 | NCT03713320 | |||
| Ts-miR Supplementation | miR-34a | MRX34 | Advanced solid tumors | Phase 1 | NCT01829971 |
| Melanoma | Phase 1 Phase 2 | NCT02862145 | |||
| miR-16 | TargomiRs | Recurrent malignant pleural mesothelioma and non-small cell lung cancer | Phase 1 | NCT02369198 | |
| miR-193a-3p | INT-1B3 | Advanced solid tumors | Phase 1 | NCT04675996 |
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