Open Access

Figure 2

image

Download original image

Apoptosis, Bcl-2 expression, and cell proliferation. The left panel shows a case of Burkitt lymphoma, characterized by extensive apoptosis, which creates a “starry sky” appearance due to phagocytosis of cell debris by the macrophages in H.E staining. Notably, Bcl-2 is not expressed, and the tumor proliferation index is extremely high. The right panel depicts a case of low-grade follicular lymphoma (FCL), in which apoptosis is rarely observed. Bcl-2 expression is abnormally high due to its dislocation to the neighborhood of immunoglobulin heavy chain (IgH), resulting in a significantly lower tumor proliferation index. All the pictures are the same magnification. Bar = 60 µm.

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.