Figure 4

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Mammary tumor progression is not inhibited by Mogat2 gene depletion. (a) The number of mammary glands with palpable tumors for Mogat2+/+PyMT (n = 19) and Mogat2−/−PyMT (n = 19) mice. Data shown are the number of tumor-bearing glands per mouse. Mammary tumors were monitored by weekly palpation. (b) Total tumor weight for Mogat2+/+PyMT (n = 10) and Mogat2−/−PyMT (n = 10) mice. (c–d) Lungs from Mogat2+/+PyMT (n = 20) and Mogat2−/−PyMT (n = 20) mice were stained with Bouin’s solution to identify metastases. Metastatic lesions are indicated by the arrows. (c) The data represents the mean total number of metastases ± SEM from both groups at 15 weeks old (d) Data represents the mean ± SEM, NS = non-significant. All mice were fed a normal diet.
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