Loss of monoacylglycerol O-acyltransferase 2 can be compensated for by diacylglycerol O-acyltransferases 1 and 2 resulting in a negligible influence on mammary cancer development found in a mouse model and verified in human tissues

Open Access

Figure 2

A relatively high-fat diet promotes obesity regardless of Mogat2 depletion. Body weight was determined in Mogat2^+/+PyMT (n = 15) and Mogat2^−/−PyMT (n = 15) mice fed with a relatively high-fat diet, as well as in the control group of Mogat2^+/+PyMT (n = 15) fed with a normal diet. Increments in body weight were found to be independent of the Mogat2 gene. NS = non-significant.

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