Issue |
Vis Cancer Med
Volume 5, 2024
|
|
---|---|---|
Article Number | 10 | |
Number of page(s) | 3 | |
DOI | https://doi.org/10.1051/vcm/2024012 | |
Published online | 03 January 2025 |
Viewpoint
Detection and characterization of circulating tumor cells and pre-metastatic cancer cells: Questions 108–109 in the 150 most important questions in cancer research and clinical oncology series
1
Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, Guangdong, China
2
Key University Laboratory of Metabolism and Health of Guangdong, Southern University of Science and Technology, Shenzhen, 518055, Guangdong, China
3
Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Southern University of Science and Technology, Shenzhen, 518055, Guangdong, China
4
Department of Pathology, School of Medicine, Southern University of Science and Technology, Shenzhen, 518055, Guangdong, China
* Corresponding authors: hongx@sustech.edu.cn; zhangwy@sustech.edu.cn
Received:
18
July
2024
Accepted:
23
November
2024
In this article, the authors raise two key questions: 108. Can we develop automated noninvasive detection coupled with single-cell omics technologies that can simultaneously identify and characterize the biological properties of circulating tumor cells using peripheral blood samples from cancer patients? 109. Can we identify cancer cells with metastatic potential in the primary tumor even before metastatic progression for more precise targeted therapies that prevent the spreading of cancer cells? The background introduction and the application potentials of answering these questions are included.
Key words: Circulating tumor cells (CTCs) / Noninvasive detection / Single-cell omics / Pre-metastatic tumor cells / Functional imaging
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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