Issue |
Vis Cancer Med
Volume 5, 2024
|
|
---|---|---|
Article Number | 4 | |
Number of page(s) | 9 | |
DOI | https://doi.org/10.1051/vcm/2024004 | |
Published online | 22 May 2024 |
Review Article
Beam range uncertainty and its clinical management in particle therapy
1
Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 231283, PR China
2
Ion Medical Research Institute, University of Science and Technology of China, Hefei, Anhui 230026, PR China
3
Department of Engineering and Applied Physics, School of Physical Sciences, University of Science and Technology of China, Hefei, Anhui 230026, PR China
* Corresponding author: hmlu@himc.org.cn
Received:
3
September
2023
Accepted:
9
April
2024
The full theoretical advantages of particle beams in external beam radiotherapy have not been fully exploited, in large part due to uncertainties of the beam range in the patient. For this reason, efforts are underway, either for more precise in-vivo detection of Bragg peak positions or for further reduction of beam range computation errors in treatment planning. Meanwhile, management of the range uncertainty issues with mitigation techniques based on existing technology is critical in providing safe and effective treatments in clinical practice. This paper briefly reviews the definition and causes of particle range uncertainty, the uncertainty estimates currently used in clinical practice, and the corresponding mitigation techniques. It is intended to provide references for clinical practices at new and existing particle therapy centers.
Key words: Range uncertainty / Particle therapy / Clinical management
Publisher note: The final statements of this article have been corrected on 3 June 2024.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.