Figure 6

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Images related to iron mineralization. a) TEM observation of iron mineralization on mitochondria and effects of HC on the intracellular distribution of lipids in A549 cells at different time points (0, 6, and 12 h). b) CT images (on a voxel size of 0.035 × 0.035 × 0.2 mm3) of lung tumors, mineralized lung tumors, lung nodules, and HC-treated lung nodules; quantified CT value of HC-treated tumors or nodules/untreated tumors or nodules (n = 3). c) Luminescence photographs of tumor-burdened mice treated with different formulations over the 3-week treatment period. d) PET/CT analysis of the treatment efficiency of different formulations (Maximum resolution of CT = 40 μm and PET <1.4 mm). e) Confocal fluorescence microscopy images of A549 and Beas-2B cells stained by intracellular pH probe, 2′,7′-bis(2-carboxyethyl)-5-(and-6)-carboxyfluorescein, acetoxymethyl ester (BCECF-AM) after time-dependent HC treatments.
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