Open Access
Table 3
Dosimetric comparison of OARs between IMRT plans and IMPT plans.
| IMPT |
IMRT |
P-value |
||
|---|---|---|---|---|
| Median (range) | Median (range) | Wilcoxon signed rank test | ||
| Heart | Dmean (cGy) | 9.524 (0.033 ~ 42.380) | 205.219 (13.059 ~ 2668.997) | 0.012 |
| Dmax (cGy) | 952.361 (0.010 ~ 4180.165) | 1465.509 (99.437 ~ 5194.389) | 0.161 | |
| Ipsilateral Lung | Dmean (cGy) | 596.527 (125.173 ~ 974.657) | 1073.826 (527.924 ~ 2997.944) | 0.036 |
| Dmax (cGy) | 5150.084 (4465.475 ~ 5744.415) | 5092.091 (4584.739 ~ 5297.524) | 0.208 | |
| V5 (%) | 31.162 (6.387 ~ 51.699) | 48.744 (17.934 ~ 98.980) | 0.069 | |
| V20 (%) | 10.224 (0.589 ~ 16.911) | 18.712 (8.740 ~ 62.213) | 0.050 | |
| V30 (%) | 4.190 (0.247 ~ 7.170) | 12.568 (0.058 ~ 38.278) | 0.050 | |
| Contralateral Lung | Dmean (cGy) | 6.149 (0.234 ~ 38.747) | 34.790 (8.092 ~ 494.343) | 0.012 |
| Dmax (cGy) | 1182.443 (6.621 ~ 2632.009) | 409.237 (92.442 ~ 4102.270) | 0.779 | |
| V5 (%) | 0.098 (0 ~ 2.086) | 0.006 (0 ~ 38.995) | 0.398 | |
| V20 (%) | 0.000 (0.000 ~ 0.005647) | 0.000 (0.000 ~ 1.113) | 0.753 | |
| V30 (%) | 0 (0 ~ 0) | 0 (0 ~ 0) | 0.068 | |
| Spinal Cord | Dmean (cGy) | 5.787 (0.000 ~ 66.194) | 138.988 (13.896 ~ 936.309) | 0.012 |
| Dmax (cGy) | 122.691 (0.000 ~ 1276.097) | 506.093 (36.456 ~ 2761.027) | 0.123 |
Significant data is presented in bold. IMPT: intensity modulated proton therapy, IMRT: intensity modulated radiotherapy, V5, V20, V30: volume receiving ≥ 5, 20, 30 Gy, respectively, Dmax: dose encompassing 2% of the volume, Dmean: mean dose.
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