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High endothelial venules in NPC tissues. High endothelial venules (HEVs) stained by MECA-79 antibody to visualize peripheral node addressin (PNAd). (A) The HEVs are indicated by arrows located in the periphery of the tumor nest (T). (B) One HEV is surrounded by tumor cells. (C) A NPC tissue section with an embolus cell cluster within a HEV (arrow).
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